I would like to know how one copes with multiple diseases including HF (20% EF). Mentally, it is a challenge for me to stay positive. I have Chronic Pancreatitis, Chronic Kidney Disease, Heart Failure due to several MI's and Prinzmetal to name a few. I also had a bad summer and came down with Pneumonia which lead to C Diff which has now lead to colitis which I was recently diagnosed. Everything is snow balling for me and though I try to stay positive.....it is very hard. Is anyone dealing with multiple issues and if so, how are you coping? I am a wife, grandmother and own a small business with my husband and find it increasingly hard to manage any of it. I am a small woman weighing 98 lbs and I find that doctors prescribe medications in full dose when I think a smaller dose is best to start. Am I wrong?